Genedata has introduced version 4.0 of Genedata Selector, a genome knowledge management solution with capabilities for reference-independent genome sequence comparisons while reducing data processing and analysis time.
Genedata Selector 4.0's comparative genomics functionalities make it possible to compare and interpret genomic variants across assemblies and sequencing approaches. At the same time, the new automated processing pipeline optimises user efficiency and lowers costs throughout the workflow, from integrating new knowledge, maintaining existing knowledge and interpreting data to generating reports.
For researchers, the comparison of variants across reference systems is a difficult and time-consuming task, while for bioinformaticians, the re-alignment of historic data to new reference genomes is a challenge. Other data management systems that store variants relative to reference assemblies do not enable the performance of analyses that span different reference systems, or between genomes that are assembled without a reference genome (for example, de novo sequencing methods).
Keeping all of the constantly accumulating variant knowledge current and accurate involves vast amounts of data, placing high demands on hardware and IT resources. As sequencing costs decrease and de novo sequencing approaches become more prevalent, there is a pressing need for knowledge management solutions with fewer limitations which reduce pressure on resources. Genedata Selector 4.0 has been specially designed to meet these challenges.
New genome assemblies and re-sequenced genomes can now be easily integrated with existing genomic knowledge through a new processing pipeline which automatically updates variant data from previous analyses. Users now have the ability to analyse genomic sequences and protein affects across any available reference assembly. This includes choosing a reference from within the user interface, or directly comparing variants independent of any reference genome.
