LabLogic has announced the latest release of the industry standard LIMS for radiolabelled metabolism studies, Debra.
Building on the functionality for environmental fate - which provides the capability to investigate the life cycle of a chemical in the environment - added with the upgrade to Debra 6. Version 6.2 offers a brand new protocol set-up for adsorption/desorption studies together with powerful and flexible reporting for all study parameters.
Other key features of the release include:
New soil dispensing options for aqueous sediment study types
Ability to convert aliquot volumes to weights by addition of a density value – aiding preparation of aliquot batches using a fixed volume
New dose unit of mg/subject – useful for low dose level eFate studies
All extraction (Trace) calculations are now shown for easy QA and verification of calculated results
Huw Loaring, Systems Director at LabLogic said: ‘A lot of the focus since Debra 6 was released has been in extending the functionality of the system to include the entire spectrum of environmental fate studies using radiolabelled test items for our customers. We are excited that Debra now covers both aerobic and anaerobic soil degradation and metabolism studies (OECD 307), soil adsorption (OECD 106), hydrolysis studies (OECD 111) and metabolism studies in water/sediment systems under aerobic and anaerobic incubation conditions (OECD 308).’
Loaring continued: ‘Additionally Debra is used in plant and crop rotation metabolism studies as well as livestock metabolism and the link with our Laura radiochromatography software allows scientists to determine the behaviour of the compound to elucidate the degradation of the applied parent test substance, as well as the formation and decline of possible metabolites all without having to take data outside of our GLP validated environment.’
Debra is used by both contract research organisations as well as pharmaceutical and agrochemical companies with Debra 6 allowing easy exchange of data between both sponsor and CRO. An easy upgrade path enables existing customers to move to the latest release.
